Sinapsos Podcast | Oncology

E12   |  10 min   |   Latest   |  Publication Link

• Podcast based on: Restaino, S.; Pellecchia, G.; Arcieri, M.; Mariuzzi, L.; Orsaria, M.; Tulisso, A.; Cesselli, D.; Bulfoni, M.; Poli, A.; Paparcura, F.; Bogani, G.; Mariani, A.; Zannoni, G.; Scambia, G.; Vizzielli, G. Alignment of Molecular Classification Between Diagnosis and Recurrence in Endometrial Cancer: Lessons from a Single-Institution Experience to Inform Future Pathways. Cancers 2026, 18, 247. https://doi.org/10.3390/cancers18020247
  Type: Article  |  Publication date: 13 January 2026
  
  
• Summary: Endometrial cancer treatment and prognosis have greatly improved thanks to advances in understanding its molecular profile. However, it is still unclear whether these molecular characteristics remain stable over time, particularly when the disease returns after initial treatment. This study explores the concordance and potential evolution of molecular classification between primary diagnosis and recurrence in endometrial cancer, building upon emerging evidence that has begun to address this question. This study explores the concordance and potential evolution of molecular classification between primary diagnosis and recurrence in endometrial cancer, building upon emerging evidence that has begun to address this question. By examining this relationship, our research provides valuable preliminary data that could guide future studies on the biological behavior of recurrent disease. These insights may ultimately contribute to more precise and personalized treatment strategies for patients with endometrial cancer.
  
  
• Keywords: molecular biology; endometrial cancer; recurrence

License and disclaimer:
Original article © 2026 by the authors. Licensed under the Creative Commons Attribution 4.0 (CC BY 4.0) license (https://creativecommons.org/licenses/by/4.0/). This episode is an AI-generated audio adaptation of the article: the script and the voices are synthetic, changes were made, and the adaptation is not endorsed by the authors, the journal, or the publisher. It may contain errors or omissions, so consult the original publication before relying on any detail. It is for educational purposes only and is not medical advice. The creators accept no liability for any use of this content.