Sinapsos Podcast | Oncology

E28   |  13 min   |   Latest   |  Publication Link

• Podcast based on: Karpes, J.B.; Liu, K.; Crawford, M.D.; Pulitano, C.; Sandroussi, C.; Laurence, J.M. Reducing Complications in Pancreaticoduodenectomy. Cancers 2026, 18, 630. https://doi.org/10.3390/cancers18040630
  Type: Review  |  Publication date: 14 February 2026
  
  
• Summary: Pancreatic surgery is one of the most complex areas of abdominal surgery, with morbidity and mortality remaining a major challenge. Despite progress in surgical techniques and perioperative care, outcomes still vary widely, and there is no consensus on how to reliably prevent major complications. This study evaluates contemporary evidence on how complications develop, how they can be detected early, and the strategies that may reduce their frequency and impact. The evaluation includes technical factors during surgery, as well as non-technical factors outside of the operating theatre that may improve safety and outcomes. The goal of this review is to guide practice and future research to improve the safety of pancreatic resection in any environment.
  
  
• Keywords: pancreaticoduodenectomy; postoperative pancreatic fistula; centralisation; failure to rescue

License and disclaimer:
Original article © 2026 by the authors. Licensed under the Creative Commons Attribution 4.0 (CC BY 4.0) license (https://creativecommons.org/licenses/by/4.0/). This episode is an AI-generated audio adaptation of the article: the script and the voices are synthetic, changes were made, and the adaptation is not endorsed by the authors, the journal, or the publisher. It may contain errors or omissions, so consult the original publication before relying on any detail. It is for educational purposes only and is not medical advice. The creators accept no liability for any use of this content.